Paul Industries designs and installs high-purity water systems across Ohio, and Ohio is the state where the two meanings of that phrase collide. Pharmaceutical high-purity water is defined by what is alive in it. Semiconductor ultrapure water is defined by what is dissolved and suspended in it at parts per billion. SEMI F63 sets specifications for advanced processing at above 18.2 megohm-centimeter resistivity, total organic carbon below 1 part per billion, silica below 0.3 parts per billion and particle counts below one per milliliter. A Water for Injection loop would fail that specification comprehensively, and it would not care.

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Two different targets Endotoxin and bioburden, against dissolved ions and nanoparticles
Semiconductor references SEMI F63 for the water, SEMI F61 for system design and operation
Advanced node figures Above 18.2 megohm-cm, TOC below 1 ppb, silica below 0.3 ppb, particles below 1 per mL
Ohio reality check The Licking County fab is now targeted at 2030 to 2031, not this decade’s first half
Industrial power 7.10 cents/kWh, 0.87x the US average of 8.13 (EIA, 2024)
Reviewed September 2026, against current state code and EIA 2024 energy data

Same phrase, two unrelated engineering problems

Ohio carries pharmaceutical and food manufacturing alongside a long-horizon semiconductor buildout, and contractors moving between them frequently assume that high-purity water experience transfers. It transfers less than anyone expects.

A pharmaceutical water system is built against biology. Water for Injection carries an endotoxin limit of 0.25 EU per milliliter in addition to chemistry limits, endotoxin comes from Gram-negative bacterial growth, and every characteristic design feature follows from preventing biofilm: hot circulating loops, sanitization regimes, drainable layouts without dead legs. Dissolved silica at 5 parts per billion is of no interest whatsoever.

A semiconductor ultrapure water system is built against chemistry and particles. The water contacts a wafer surface where a single nanometre-scale particle can destroy a die and where trace dissolved metals or silica leave residues that alter device behavior. Resistivity above 18.2 megohm-centimeter means essentially every ion has been removed. Organic carbon below one part per billion is two to three orders of magnitude tighter than the compendial limit a pharmaceutical system works to. Particle counts are specified in counts per milliliter at sizes no pharmaceutical monograph addresses.

The consequences reach into every part of the design and they frequently point in opposite directions.

Heat, which is a pharmaceutical system’s primary microbial control, is a liability in ultrapure water, because hot water is more aggressive toward the materials containing it and extraction from surfaces rises with temperature. Ultrapure systems run cold or ambient and control biology by other means: ultraviolet treatment, continuous high-velocity recirculation with no stagnant volume anywhere, and ultrafiltration at the point of use.

Polishing that a pharmaceutical system would consider finished is where an ultrapure system begins. After reverse osmosis and deionization, an ultrapure loop adds ultraviolet for organic reduction, polishing resin, degasification and final filtration, and then keeps polishing continuously because the water degrades the moment it stops moving.

And monitoring is continuous rather than periodic. Resistivity, total organic carbon and particle counts are measured inline and in real time, because a specification measured in parts per billion cannot be defended by a sample taken once a shift.

The two specifications side by side

Pharmaceutical compendial water compared with semiconductor ultrapure water
 Pharmaceutical WFI or Purified WaterSemiconductor UPW
Governing documentsUSP 643, USP 645, endotoxin limit for WFISEMI F63 for water, SEMI F61 for system design
Defining threatMicrobial growth and endotoxinDissolved ions, organics, silica, nanoparticles
ResistivityConductivity within a staged limitAbove 18.2 megohm-cm
Organic carbonCompendial limitBelow 1 ppb for advanced nodes
Temperature strategyOften hot, for microbial controlCold or ambient; heat increases extraction
MonitoringSampling program with laboratory resultsContinuous inline measurement
Distribution materialStainless steelHigh-purity fluoropolymer, not stainless
Annual electricity for continuous treatment and recirculation at Ohio’s 7.10 cents/kWh
Continuous loadPer yearOver ten years
25 kW$15,549$155,490
50 kW$31,098$310,980
100 kW$62,196$621,960

Ohio power at 0.87 times the national average makes continuous recirculation inexpensive to run, which matters because an ultrapure system has no alternative to running continuously. Stagnant ultrapure water degrades quickly, so the loop never stops, and a state with cheap power is a comparatively forgiving place to operate one.

What the Ohio semiconductor timeline means for your plant

It is worth being straightforward about this, because a good deal of published material is not. The Licking County semiconductor project is real and substantial, with more than five billion dollars invested by the end of 2025 and total investment including contract commitments closer to seven billion. It is also considerably slower than originally announced: the first fabrication module is now targeted for completion around 2030 to 2031, with the second roughly a year later, after the company concluded it had invested too much too soon and slowed construction.

What that means practically is that Ohio ultrapure water demand over the next several years comes mainly from existing electronics, specialty manufacturing, laboratory and research installations, and from suppliers positioning ahead of a later ramp, rather than from a fab consuming water at production scale. Anyone selling you urgency on the basis of an imminent fab is selling a timeline that the company itself has moved.

Frequently asked questions

Do you install high-purity water systems in Ohio?

Yes, statewide across Columbus, Cleveland, Cincinnati, Dayton and Toledo, covering pharmaceutical compendial water, food and beverage process water, and ultrapure water for electronics and laboratory applications. The first question we ask is which specification governs, because pharmaceutical and semiconductor high-purity water are different engineering problems that share a name.

How is ultrapure water different from Water for Injection?

Almost entirely. WFI is defined against biology, with an endotoxin limit driving hot loops and sanitization. Ultrapure water is defined against chemistry and particles: above 18.2 megohm-centimeter resistivity, organic carbon below one part per billion and silica below 0.3 parts per billion for advanced processing under SEMI F63. A compliant WFI loop would fail those limits comprehensively and has no reason to meet them.

Why is ultrapure water not run hot?

Because heat is the pharmaceutical answer to a problem ultrapure systems solve differently, and it creates one they cannot tolerate. Hot high-purity water is more aggressive toward the materials containing it and extraction from surfaces increases with temperature, which works directly against a parts-per-billion specification. Ultrapure systems run cold or ambient and control biology with ultraviolet treatment, continuous high-velocity recirculation and point-of-use filtration.

Which standards apply to a semiconductor water system?

SEMI F63 is the guide for ultrapure water used in semiconductor processing and is used to set purchasing criteria, process control parameters and quality expectations for supplied water. SEMI F61 covers the design and operation of the system itself. Between them they address water quality, system design, material selection and maintenance, all assuming continuous monitoring.

Why is monitoring continuous rather than sampled?

Because a specification expressed in parts per billion cannot be defended by a sample taken once a shift. Resistivity, total organic carbon and particle counts are measured inline in real time, so that a degradation is caught as it happens rather than discovered in a laboratory result after the affected wafers have been processed.

Can a pharmaceutical water contractor build an ultrapure system?

Not on pharmaceutical experience alone, and the difference is worth understanding before choosing a contractor. The welding discipline, the documentation habits and the understanding of cleanability transfer well. What does not transfer is material selection, the polishing train, the temperature strategy and the monitoring philosophy, all of which differ fundamentally. Ask any contractor which standard they are designing to before anything else.

What does the polishing loop actually do?

It continues purifying water that a pharmaceutical system would already consider finished. After reverse osmosis and deionization, an ultrapure loop adds ultraviolet for organic reduction, polishing resin, degasification and final filtration, and keeps doing so continuously, because ultrapure water degrades as soon as it stops moving and picks up whatever its surroundings can give it.

Is the Intel project driving demand right now?

Less than most coverage suggests. The project is real, with more than five billion dollars invested by the end of 2025 and closer to seven billion including contract commitments, but the first fabrication module is now targeted around 2030 to 2031 after the company slowed construction. Near-term Ohio demand comes from existing electronics, specialty manufacturing and laboratory installations rather than from a fab at production scale.

Does Ohio energy cost affect the design?

It helps. At 7.10 cents per kilowatt-hour against a national average of 8.13 (EIA, 2024), a 50 kW continuous load costs about $31,098 a year. That matters because an ultrapure system has no option but to run continuously, since stagnant ultrapure water degrades quickly. Cheap power makes Ohio a comparatively forgiving place to operate one.

How do I get a quote for an Ohio water system?

Use the form on this page or call 201-450-8280. The most useful first answer is which specification governs and who set it, because that determines everything downstream. Beyond that: peak rather than average demand, the number of points of use, a current feed water analysis, and whether the application is pharmaceutical, food, electronics or laboratory.

How are dissolved gases removed?

By membrane degasification, usually, which strips dissolved oxygen and carbon dioxide through a gas-permeable membrane under vacuum. Dissolved oxygen matters because it affects surface reactions on the wafer, and carbon dioxide because it depresses resistivity. Neither is addressed by the ion exchange and filtration that handle the rest of the contamination.

How are particles measured at these sizes?

With online instruments capable of counting at sizes far below what a pharmaceutical system monitors, because the particles of concern are a fraction of the feature sizes on the wafer. This is one of the clearest illustrations of the difference: a water system that is exemplary by pharmaceutical standards may be unusable for semiconductor purposes.

Do metals need controlling at trace levels?

At parts-per-trillion for the elements that matter, because metallic contamination on a wafer surface causes device failures. That drives material selection throughout, since any component contributing metal ions, including stainless steel, is unsuitable in the final loop. It is the main reason these systems are built from fluoropolymers rather than steel.

Why is velocity a design requirement?

Because continuous turbulent recirculation is what prevents contamination accumulating anywhere in the loop, and in a system with no chemical or thermal sanitisation, flow is the primary control. The velocity requirement applies at every point including the branches, which is why these systems are designed with no stagnant sections at all.

Can there be any dead legs?

Effectively none, and the tolerance is far tighter than sanitary practice. A branch that cannot be swept will contribute contamination continuously in a system where the entire design intent is to add nothing to the water. Points of use are arranged so flow passes them rather than terminating at them, which shapes the whole distribution layout.

Do bacteria matter in ultrapure water?

Yes, though for different reasons than in pharmaceutical water. Organisms contribute particles and organic carbon, and their fragments do not disappear when they die. The control is continuous flow, ultraviolet treatment and final ultrafiltration rather than thermal or chemical sanitisation, which these materials and this purity level do not accommodate easily.

How much water does a facility like this use?

A great deal, which is why reclaim is standard practice rather than an environmental gesture. Rinse water from many process steps is captured, segregated by contamination type, treated and returned, so that the facility’s draw is a fraction of its consumption. Designing the reclaim architecture is a major part of the water system’s scope.

Is reclaim water returned to ultrapure quality?

Some streams are, where the contamination is light and well characterised, while others are treated to lower grades for non-critical uses. Segregation at source is what makes this possible: mixing a lightly contaminated rinse with a chemically loaded stream destroys the value of both. That segregation has to be designed into the drainage from the start.

How is such a system qualified?

By demonstrating it meets every parameter continuously at every point of use under real demand, which takes time because the system must first clean itself up. New ultrapure systems typically require an extended flushing and recirculation period before quality stabilises, and that period is a real part of the project schedule rather than a commissioning formality.

Is the regional semiconductor investment driving demand?

Central Ohio has attracted very large semiconductor investment, and the demand extends well beyond the fabs to the supplier and support facilities around them, which need high-purity gases, chemical distribution, ultrapure water and controlled environments. Paul delivers that supporting-tier work as well as the work inside the fabs themselves.

What is the commonest mistake when crossing between these worlds?

Assuming that higher pharmaceutical purity requirements imply competence at semiconductor purity, or the reverse. They are different specifications with different materials, different joints, different contaminants and different acceptance tests. The failures we are asked to look at usually come from a competent contractor applying the right practice from the wrong industry.

How is the reclaim architecture designed?

By segregating drains at source according to what each process step contributes, so that lightly contaminated rinse water stays separate from chemically loaded streams. That segregation is a drainage design decision made very early, and it cannot be retrofitted cheaply because it means rerouting drainage under an operating facility.

What happens during an extended shutdown?

The loop keeps recirculating if at all possible, because flow is the control and a stagnant ultrapure system degrades quickly and takes a long time to recover. Where a shutdown is unavoidable, the restart involves an extended flush and recirculation period before quality returns, which has to be planned into the production schedule.

Does the distribution material contribute contamination?

Continuously, at some level, which is why material selection is so restrictive. Every wetted surface extracts something into water this pure, so the specification chooses materials that contribute least and the polishing loop removes what they contribute. Stainless steel is excluded from the final loop for exactly this reason.

How are point-of-use connections arranged?

So that flow passes the connection rather than terminating at it, keeping the branch swept at all times. Tool connections are made with fittings that maintain the internal surface quality and avoid crevices, and the valve arrangement is chosen so that no stagnant volume sits between the loop and the point of use.

Planning a high-purity or ultrapure water system in Ohio?

Tell us which specification governs and who set it. Call 201-450-8280 or use the form below.

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